Human Sperm Proacrosin is Activated During Sperm Capacitation Process.
نویسندگان
چکیده
منابع مشابه
Membrane hyperpolarization during human sperm capacitation.
Sperm capacitation is a complex and indispensable physiological process that spermatozoa must undergo in order to acquire fertilization capability. Spermatozoa from several mammalian species, including mice, exhibit a capacitation-associated plasma membrane hyperpolarization, which is necessary for the acrosome reaction to occur. Despite its importance, this hyperpolarization event has not been...
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Sperm membranes have an unusual lipidic composition which is distinct from those of mammalian somatic cells. They have high levels of plasmalogens, a kind of ether-linked lipids, and a high content of polyunsaturated fatty acyl groups. Plasmalogens may form non-diffusible membrane regions or domains, whereas polyunsaturated ethanolamine plasmalogens are known to destabilize the lipidic bilayer....
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In order to be able to fertilize oocytes, human sperm must undergo a series of morphological and structural alterations, known as capacitation. It has been shown that the production of endogenous sperm reactive oxygen species (ROS) plays a key role in causing cells to undergo a massive acrosome reaction (AR). Astaxanthin (Asta), a photo-protective red pigment belonging to the carotenoid family,...
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The sperm cell has a characteristic polarized morphology and its surface is also highly differentiated into different membrane domains. Junctional protein ring structures seal the surface of the mid-piece from the head and the tail respectively and probably prevent random diffusion of membrane molecules over the protein rings. Despite the absence of such lateral diffusion-preventing structures,...
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Spermatozoa after being deposited in the female reproductive tract spend a considerable time in this foreign environment prior to fertilization of the oocyte. Chang and Austin independently observed1,2 that this time spent by the spermatozoa in the female tract is not consequential but a necessary event in the life cycle of the male gamete, and Austin2 first called this maturation period of spe...
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ژورنال
عنوان ژورنال: The Japanese Journal of Urology
سال: 1995
ISSN: 0021-5287,1884-7110
DOI: 10.5980/jpnjurol.86.228_4